To get to Caltanissetta from Città di Castello you can take a flight from Perugia Sant'Egidio Airport, which is the closest airport to Città di Castello, and arrive at Comiso Airport, the airport the best serves Caltanissetta. The average price for a Città di Castello to Caltanissetta flight is 248€, but you can find low cost flights as well, with prices starting from 95€. Getting from Città di Castello to Caltanissetta by flight takes about 1 hour on average; however, you need to consider the time to get to the airport and pass the security checks. You can count on 44 daily connections between Città di Castello and Caltanissetta provided by Vueling Airlines, Air Italy, and Ryanair. Comiso Airport is the closest airport to Caltanissetta and is 118 kilometers away from the city center; you can get to Caltanissetta in about 3 hours thanks to airport shuttles from Comiso Airport to Caltanissetta.