Travel from Milan to Ascoli Piceno and discover this Marche city of 42.000 inhabitants. The distance from Milan to Ascoli Piceno is 735 kilometers; with Wanderio you can compare the available trains, buses, and flights to get from Milan to Ascoli Piceno, so that you can organize your trip choosing the fastest route, the most comfortable or the cheapest one. You can choose among different choices and organize your trip according to your needs, depending on whether you are looking for the fastest, the most comfortable or perhaps the cheapest travel solution. For example, by choosing a flight from Milan to Ascoli Piceno, you’ll get to your destination in about 1 hour on average; flight ticket prices start from 74 €. Going from Milan to Ascoli Piceno by train instead? Prices for your ticket start from 64 € and the train journey takes about 5 hours on average.