Travel from Rome to Osimo and discover this Marche city of 17.000 inhabitants. The distance from Rome to Osimo is 313 kilometers; with Wanderio you can compare the available trains and flights to get from Rome to Osimo, so that you can organize your trip choosing the fastest route, the most comfortable or the cheapest one. You can choose among different choices and organize your trip according to your needs, depending on whether you are looking for the fastest, the most comfortable or perhaps the cheapest travel solution. For example, by choosing a flight from Rome to Osimo, you’ll get to your destination in about 1 hour on average; flight ticket prices start from 95 €. Going from Rome to Osimo by train instead? Prices for your ticket start from 17 € and the train journey takes about 3 hours on average.