Acqui Terme to Marsala trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Acqui Terme and arrive at Mozia-Birgi every about 2 hours on average. If travelling with Trenitalia, you need to know the Acqui Terme to Marsala train schedule: the first train leaves at 09:42, while the last ride is at 20:49. A Acqui Terme to Marsala train cost about 125.7 €. But how long is the train ride from Acqui Terme to Marsala? Your journey takes about 4 hours on average.