Acqui Terme to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 5 daily rides to get from Acqui Terme to Niscemi. The first train to Niscemi leaves from Acqui Terme at 09:42 and the last train departs at 20:49. If you choose a local train the trip lasts on average 00:56 hours. For your trip from Acqui Terme to Niscemi by train you can choose to leave from one of Acqui Terme main stations: Acqui Terme On Wanderio you can compare all schedules, fares and railway companies to Niscemi and book the best itinerary starting from Acqui Terme.