Acqui Terme to Ragusa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Acqui Terme and arrive at Ragusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Acqui Terme to Ragusa train schedule: the first train leaves at 13:16, while the last ride is at 19:37. A Acqui Terme to Ragusa train cost about 78.35 €. But how long is the train ride from Acqui Terme to Ragusa? Your journey takes about 8 hours on average.