Afragola to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casoria-Afragola, Reggio di Calabria Centrale and arrive at Caltanissetta Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Afragola to Caltanissetta train schedule: the first train leaves at 08:46, while the last ride is at 21:58. A Afragola to Caltanissetta train cost about 11.9 €. But how long is the train ride from Afragola to Caltanissetta? Your journey takes about 10 hours on average.