Afragola to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casoria-Afragola and arrive at Palermo Notarbartolo every about 4 hours on average. If travelling with Trenitalia, you need to know the Afragola to Palermo train schedule: the first train leaves at 08:46, while the last ride is at 22:30. A Afragola to Palermo train cost about 66.4 €. But how long is the train ride from Afragola to Palermo? Your journey takes about 12 hours on average.