Agrigento to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Agrigento Centrale and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Agrigento to Syracuse train schedule: the first train leaves at 06:14, while the last ride is at 15:14. A Agrigento to Syracuse train cost about 18.10 €. But how long is the train ride from Agrigento to Syracuse? Your journey takes about 6 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Agrigento to Syracuse and find low cost tickets starting from 14 €!