Alessandria to Messina trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 5 daily rides to get from Alessandria to Messina. Trains leave from Alessandria and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Alessandria to Messina train schedule: the first train leaves at 13:31, while the last ride is at 22:59. A Alessandria to Messina train cost about 109.0 €. But how long is the train ride from Alessandria to Messina? Your journey takes about 16 hours on average. Thanks to Trenitalia offers, you can save on your trip from Alessandria to Messina and find prices starting from 69 €!