Alpignano to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Alpignano and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Alpignano to Alessandria train schedule: the first train leaves at 05:25, while the last ride is at 20:55. A Alpignano to Alessandria train cost about 8.7 €. But how long is the train ride from Alpignano to Alessandria? Your journey takes about 2 hours on average.