Alpignano to Brindisi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Alpignano and arrive at Brindisi every 60 minutes on average. If travelling with Trenitalia, you need to know the Alpignano to Brindisi train schedule: the first train leaves at 07:55, while the last ride is at 23:25. A Alpignano to Brindisi train cost about 71.6 €. But how long is the train ride from Alpignano to Brindisi? Your journey takes about 13 hours on average.