Alpignano to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Alpignano and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Alpignano to Palermo train schedule: the first train leaves at 10:25, while the last ride is at 20:55. A Alpignano to Palermo train cost about 114.3 €. But how long is the train ride from Alpignano to Palermo? Your journey takes about 21 hours on average.