Anzio to Cassino trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Villa Claudia and arrive at Cassino every 60 minutes on average. If travelling with Trenitalia, you need to know the Anzio to Cassino train schedule: the first train leaves at 05:03, while the last ride is at 22:13. A Anzio to Cassino train cost about 10.7 €. But how long is the train ride from Anzio to Cassino? Your journey takes about 3 hours on average.