Anzio to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Villa Claudia and arrive at Comiso every about 4 hours on average. If travelling with Trenitalia, you need to know the Anzio to Comiso train schedule: the first train leaves at 06:06, while the last ride is at 20:23. A Anzio to Comiso train cost about 83.65 €. But how long is the train ride from Anzio to Comiso? Your journey takes about 17 hours on average.