Anzio to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Villa Claudia and arrive at Mazara del Vallo every about 6 hours on average. If travelling with Trenitalia, you need to know the Anzio to Mazara del Vallo train schedule: the first train leaves at 18:23, while the last ride is at 20:23. A Anzio to Mazara del Vallo train cost about 109.9 €. But how long is the train ride from Anzio to Mazara del Vallo? Your journey takes about 18 hours on average.