Anzio to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Villa Claudia and arrive at Palermo Notarbartolo every about 3 hours on average. If travelling with Trenitalia, you need to know the Anzio to Palermo train schedule: the first train leaves at 06:06, while the last ride is at 20:23. A Anzio to Palermo train cost about 82.6 €. But how long is the train ride from Anzio to Palermo? Your journey takes about 14 hours on average.