Arzignano to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 2 daily rides to get from Arzignano to Niscemi. Trains leave from Montebello and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Arzignano to Niscemi train schedule: the first train leaves at 17:35, while the last ride is at 22:35. A Arzignano to Niscemi train cost about 132.75 €. But how long is the train ride from Arzignano to Niscemi? Your journey takes about 23 hours on average.