Asti to Messina trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 5 daily rides to get from Asti to Messina. If travelling with Trenitalia, you need to know the Asti to Messina train schedule: the first train leaves at 04:32, while the last ride is at 22:36. A Asti to Messina train cost about 78.25 €. But how long is the train ride from Asti to Messina? Your journey takes about 16 hours on average.