Avezzano to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Avezzano and arrive at Comiso every about 6 hours on average. If travelling with Trenitalia, you need to know the Avezzano to Comiso train schedule: the first train leaves at 17:21, while the last ride is at 19:03. A Avezzano to Comiso train cost about 110.4 €. But how long is the train ride from Avezzano to Comiso? Your journey takes about 19 hours on average.