Avezzano to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Avezzano and arrive at Niscemi every about 4 hours on average. If travelling with Trenitalia, you need to know the Avezzano to Niscemi train schedule: the first train leaves at 09:20, while the last ride is at 19:03. A Avezzano to Niscemi train cost about 103.55 €. But how long is the train ride from Avezzano to Niscemi? Your journey takes about 23 hours on average.