Brindisi to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Brindisi to Alpignano train schedule: the first train leaves at 04:00, while the last ride is at 22:38. A Brindisi to Alpignano train cost about 71.6 €. But how long is the train ride from Brindisi to Alpignano? Your journey takes about 12 hours on average.