Brindisi to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at Caltanissetta Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Brindisi to Caltanissetta train schedule: the first train leaves at 20:38, while the last ride is at 20:38. A Brindisi to Caltanissetta train cost about 67.4 €. But how long is the train ride from Brindisi to Caltanissetta? Your journey takes 1 minute on average.