Brindisi to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at Enna every about 6 hours on average. If travelling with Trenitalia, you need to know the Brindisi to Enna train schedule: the first train leaves at 20:38, while the last ride is at 20:38. A Brindisi to Enna train cost about 65.75 €. But how long is the train ride from Brindisi to Enna? Your journey takes about 23 hours on average.