Brindisi to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brindisi and arrive at Trieste Centrale every about 1 hour on average. If travelling with Trenitalia, you need to know the Brindisi to Trieste train schedule: the first train leaves at 04:00, while the last ride is at 22:38. A Brindisi to Trieste train cost about 82.9 €. But how long is the train ride from Brindisi to Trieste? Your journey takes about 12 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Brindisi to Trieste and find low cost tickets starting from 62 €!