Brixen to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Bressanone Brixen and arrive at Messina Centrale every about 3 hours on average. If travelling with Trenitalia, you need to know the Brixen to Messina train schedule: the first train leaves at 16:25, while the last ride is at 20:25. A Brixen to Messina train cost about 102.95 €. But how long is the train ride from Brixen to Messina? Your journey takes about 16 hours on average.