Brixen to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Bressanone Brixen and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Brixen to Niscemi train schedule: the first train leaves at 16:25, while the last ride is at 20:25. A Brixen to Niscemi train cost about 132.6 €. But how long is the train ride from Brixen to Niscemi? Your journey takes about 1 hour on average.