Brixen to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Bressanone Brixen and arrive at Palermo Notarbartolo every about 3 hours on average. If travelling with Trenitalia, you need to know the Brixen to Palermo train schedule: the first train leaves at 13:55, while the last ride is at 20:25. A Brixen to Palermo train cost about 119.75 €. But how long is the train ride from Brixen to Palermo? Your journey takes about 17 hours on average.