Brixen to Sesto San Giovanni trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Bressanone Brixen and arrive at Sesto S. Giovanni every about 1 hour on average. If travelling with Trenitalia, you need to know the Brixen to Sesto San Giovanni train schedule: the first train leaves at 06:55, while the last ride is at 18:25. A Brixen to Sesto San Giovanni train cost about 26.2 €. But how long is the train ride from Brixen to Sesto San Giovanni? Your journey takes about 5 hours on average.