Caltagirone to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caltagirone and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Caltagirone to Messina train schedule: the first train leaves at 07:52, while the last ride is at 15:30. A Caltagirone to Messina train cost about 9.7 €. But how long is the train ride from Caltagirone to Messina? Your journey takes about 4 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Caltagirone to Messina and find low cost tickets starting from 10 €!