Caltanissetta to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caltanissetta Centrale and arrive at Palermo Notarbartolo every about 1 hour on average. If travelling with Trenitalia, you need to know the Caltanissetta to Palermo train schedule: the first train leaves at 05:02, while the last ride is at 18:46. A Caltanissetta to Palermo train cost about 8.3 €. But how long is the train ride from Caltanissetta to Palermo? Your journey takes about 2 hours on average.