Caltanissetta to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caltanissetta Centrale and arrive at Varese every about 2 hours on average. If travelling with Trenitalia, you need to know the Caltanissetta to Varese train schedule: the first train leaves at 05:40, while the last ride is at 17:51. A Caltanissetta to Varese train cost about 92.9 €. But how long is the train ride from Caltanissetta to Varese? Your journey takes about 12 hours on average.