Casa Santa to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Trapani and arrive at Avola every about 6 hours on average. If travelling with Trenitalia, you need to know the Casa Santa to Avola train schedule: the first train leaves at 05:43, while the last ride is at 05:43. A Casa Santa to Avola train cost about 50.8 €. But how long is the train ride from Casa Santa to Avola? Your journey takes about 12 hours on average.