Casa Santa to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Trapani and arrive at Noto every about 6 hours on average. If travelling with Trenitalia, you need to know the Casa Santa to Noto train schedule: the first train leaves at 05:43, while the last ride is at 05:43. A Casa Santa to Noto train cost about 110.55 €. But how long is the train ride from Casa Santa to Noto? Your journey takes about 14 hours on average.