Casa Santa to Vasto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Trapani and arrive at Porto di Vasto every about 12 hours on average. If travelling with Trenitalia, you need to know the Casa Santa to Vasto train schedule: the first train leaves at 17:48, while the last ride is at 17:48. A Casa Santa to Vasto train cost about 213.1 €. But how long is the train ride from Casa Santa to Vasto? Your journey takes about 20 hours on average.