Casa Santa to Venice trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Trapani, Napoli Centrale and arrive at Venezia S. Lucia every about 2 hours on average. If travelling with Trenitalia, you need to know the Casa Santa to Venice train schedule: the first train leaves at 05:43, while the last ride is at 09:38. A Casa Santa to Venice train cost about 117.8 €. But how long is the train ride from Casa Santa to Venice? Your journey takes about 13 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Casa Santa to Venice and find low cost tickets starting from 22 €!