Casalecchio di Reno to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casalecchio di Reno and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Casalecchio di Reno to Alessandria train schedule: the first train leaves at 07:04, while the last ride is at 20:14. A Casalecchio di Reno to Alessandria train cost about 19.75 €. But how long is the train ride from Casalecchio di Reno to Alessandria? Your journey takes about 5 hours on average.