Casarano to Milazzo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Lecce and arrive at Milazzo every about 12 hours on average. If travelling with Trenitalia, you need to know the Casarano to Milazzo train schedule: the first train leaves at 07:15, while the last ride is at 07:15. A Casarano to Milazzo train cost about 47.6 €. But how long is the train ride from Casarano to Milazzo? Your journey takes about 13 hours on average.