Casarano to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 1 daily rides to get from Casarano to Niscemi. Trains leave from Lecce and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Casarano to Niscemi train schedule: the first train leaves at 22:30, while the last ride is at 22:30. A Casarano to Niscemi train cost about 138.15 €. But how long is the train ride from Casarano to Niscemi? Your journey takes about 23 hours on average.