Cascina to Niscemi trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 2 daily rides to get from Cascina to Niscemi. Trains leave from S. Frediano a Settimo and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Cascina to Niscemi train schedule: the first train leaves at 01:47, while the last ride is at 18:45. A Cascina to Niscemi train cost about 112.15 €. But how long is the train ride from Cascina to Niscemi? Your journey takes about 21 hours on average.