Cascina to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Frediano a Settimo and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Cascina to Syracuse train schedule: the first train leaves at 08:12, while the last ride is at 23:06. A Cascina to Syracuse train cost about 97.2 €. But how long is the train ride from Cascina to Syracuse? Your journey takes about 17 hours on average.