Caserta to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caserta and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the Caserta to Comiso train schedule: the first train leaves at 21:43, while the last ride is at 21:43. A Caserta to Comiso train cost about 73.7 €. But how long is the train ride from Caserta to Comiso? Your journey takes about 15 hours on average.