Caserta to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caserta and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Caserta to Syracuse train schedule: the first train leaves at 08:41, while the last ride is at 21:43. A Caserta to Syracuse train cost about 57.7 €. But how long is the train ride from Caserta to Syracuse? Your journey takes about 12 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Caserta to Syracuse and find low cost tickets starting from 59 €!