Cassino to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cassino and arrive at Alpignano every about 2 hours on average. If travelling with Trenitalia, you need to know the Cassino to Alpignano train schedule: the first train leaves at 06:20, while the last ride is at 21:17. A Cassino to Alpignano train cost about 63.3 €. But how long is the train ride from Cassino to Alpignano? Your journey takes about 9 hours on average.