Cassino to Ragusa trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cassino and arrive at Ragusa every about 6 hours on average. If travelling with Trenitalia, you need to know the Cassino to Ragusa train schedule: the first train leaves at 07:17, while the last ride is at 18:30. A Cassino to Ragusa train cost about 70.7 €. But how long is the train ride from Cassino to Ragusa? Your journey takes about 17 hours on average.