Castelvetrano to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Castelvetrano and arrive at Siracusa every about 3 hours on average. If travelling with Trenitalia, you need to know the Castelvetrano to Syracuse train schedule: the first train leaves at 05:02, while the last ride is at 10:54. A Castelvetrano to Syracuse train cost about 19.1 €. But how long is the train ride from Castelvetrano to Syracuse? Your journey takes about 10 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Castelvetrano to Syracuse and find low cost tickets starting from 20 €!