Cento to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Pietro in Casale, Salerno and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Cento to Messina train schedule: the first train leaves at 00:09, while the last ride is at 22:01. A Cento to Messina train cost about 98.95 €. But how long is the train ride from Cento to Messina? Your journey takes about 12 hours on average. If you need to travel this week, prices start from 45.50€.