Cesena to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cesena and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the Cesena to Niscemi train schedule: the first train leaves at 18:16, while the last ride is at 22:16. A Cesena to Niscemi train cost about 135.85 €. But how long is the train ride from Cesena to Niscemi? Your journey takes about 23 hours on average.