Cesena to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cesena and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Cesena to Syracuse train schedule: the first train leaves at 08:24, while the last ride is at 23:00. A Cesena to Syracuse train cost about 98.1 €. But how long is the train ride from Cesena to Syracuse? Your journey takes about 18 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Cesena to Syracuse and find low cost tickets starting from 84 €!