Cesenatico to Manfredonia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Cesenatico and arrive at Manfredonia every about 3 hours on average. If travelling with Trenitalia, you need to know the Cesenatico to Manfredonia train schedule: the first train leaves at 10:05, while the last ride is at 22:20. A Cesenatico to Manfredonia train cost about 46.7 €. But how long is the train ride from Cesenatico to Manfredonia? Your journey takes about 7 hours on average.